Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01931-0030-0000-9 |
Chemical Name: | Cyclophosphamide monohydrate |
CASRN: | 6055-19-2 |
NTP Study Type: | Genetic Toxicology - Drosophila Germ Cell Mutagenicity |
NTP Study ID: | 788617_RT |
Study Result: | Positive |
You may also view: Sex-Linked Recessive Lethal Data for this study.
Route of Exposure | Dose ppm | Solvent | No. RTs / No. tests per sperm batch (in days of storage *) | Total No. of Translocations | Translocation Frequency (%) | |||||
---|---|---|---|---|---|---|---|---|---|---|
0-3 | 3-7 | 7-10 | 10-14 | 14-17 | 17-20 | |||||
Test Chemical | 8000 | Distilled Water | 2/2773 | 0/2788 | 0/2816 | 1/2471 | 0/1020 | 0/223 | 3/12091 | 0.02 |
Vehicle Control | 0 | Distilled Water | 0/273 | 0/264 | 0/283 | 0/271 | 0/106 | 0/8 | 0/1205 | 0.00 |
Days of Storage: The number of days sperm were stored in the female before testing.