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Study Information
Study Attribute Value
CEBS Accession Number: 002-01494-0011-0000-2
Chemical Name: 4-Chloro-o-phenylenediamine
CASRN: 95-83-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 970086_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 06/12/84 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)
n SCE / Cell
(Mean ± SEM)
Pairwise P
Vehicle Control Corn Oil
 0         
8 4.87 ± 0.351
Test Chemical 4-Chloro-o-phenylenediamine
100         
4 5.61 ± 0.535
 
200         
4 5.17 ± 0.424
 
400         
4 5.84 ± 0.806
Positive Control Dimethylbenzanthracene
10         
8 12.41 ± 0.603


Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed